DiscoverMeSsy with Christina Applegate & Jamie-Lynn Sigler
MeSsy with Christina Applegate & Jamie-Lynn Sigler
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MeSsy with Christina Applegate & Jamie-Lynn Sigler

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On this podcast, Christina Applegate and Jamie-Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.

25 Episodes
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Ed O'Neill

Ed O'Neill

2024-08-2701:15:323

This week, Christina and Jamie are joined by Ed O’Neill. They share memories from “Married... with Children,” discuss how their friendship has grown, the importance of humor, and much more. Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Honeylove - Get 20% OFF @honeylove by going to honeylove.com/messy #honeylovepod LMNT - Get your free LMNT Sample Pack with any purchase at DrinkLMNT.com/MESSY . Also try the new LMNT Sparkling — a bold, 16-ounce can of sparkling electrolyte water. OneSkin - Get 15% off OneSkin with the code MESSY  at https://www.oneskin.co/ #oneskinpod
I Love When People Cancel

I Love When People Cancel

2024-08-2001:07:562

This week, Christina and Jamie discuss the joy of missing out, pushing past your limit, feeling forced to be a certain way because of circumstance, and more. This episode was recorded April 2024. Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Jenni Kayne -Find your forever pieces @jennikayne and get 15% off with promo code MESSY15 at jennikayne.com/MESSY15 #jennikaynepartner LMNT -Get your free LMNT Sample Pack with any purchase at DrinkLMNT.com/MESSY . Also try the new LMNT Sparkling — a bold, 16-ounce can of sparkling electrolyte water. Zoc Doc - Stop putting off those doctors appointments and go to Zocdoc.com/MESSY to find and instantly book a top-rated doctor today. Peloton - Get yourself moving with Peloton at onepeloton.com/running. That’s Peloton at onepeloton.com/running
Robin Roberts

Robin Roberts

2024-08-1301:15:242

This week, Christina and Jamie are joined by Robin Roberts. Robin shares what she learned from being both a patient and a caregiver. They also discuss not being defined by what you're going through, the importance of support systems for caregivers, the power of sharing authentically, and more. Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This show is sponsored by: Lume - Control Body Odor ANYWHERE with @lumedeodorant and get 15% off with promo code MESSY at LumeDeodorant.com #lumepod. BetterHelp - This episode is sponsored by/brought to you by BetterHelp. Give online therapy a try at betterhelp.com/messy and get on your way to being your best self. Lolavie - Get 15% off LolaVie with code MESSY at https://www.lolavie.com/MESSY! #lolaviepod Peloton - Get moving with Peloton at onepeloton.com/running. That’s Peloton at onepeloton.com/running
The Power of Beau

The Power of Beau

2024-08-0658:513

This week, Jamie shares an update about what's been going on with her son, Beau. She and Christina also discuss the power of mothers, why it's crucial to speak up and trust your intuition, and more. This episode was recorded on August 2, 2024. Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: BetterHelp - This episode is sponsored by/brought to you by BetterHelp. Give online therapy a try at betterhelp.com/messy and get on your way to being your best self. Fatty15 - Fatty15 is on a mission to replenish your C15 levels and restore your long-term health.  You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/messy and using code MESSY at checkout. Peloton: Get yourself moving with Peloton at onepeloton.com/running. That’s Peloton at onepeloton.com/running
See Ya Shame!

See Ya Shame!

2024-07-3055:363

This week, Christina and Jamie discuss aging, the brief moments that have a big impact, how to deal with shame, and more. Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: AG1: It’s easy and satisfying to start your journey with AG1. Try AG1 and get a FREE 1-year supply of Vitamin D3K2 AND 5 free AG1 Travel Packs with your first purchase at drinkAG1.com/messy.  LMNT: Get your free LMNT Sample Pack with any purchase at DrinkLMNT.com/MESSY . Also try the new LMNT Sparkling — a bold, 16-ounce can of sparkling electrolyte water.” Babbel: Right now get up to 60% off your Babbel subscription - but only for our listeners - at Babbel.com/MESSY  Rules and restrictions may apply. Peloton: Get yourself moving with Peloton at onepeloton.com/running. That’s Peloton at onepeloton.com/running
Reverend Michael Beckwith

Reverend Michael Beckwith

2024-07-2301:10:23

This week, Christina and Jamie are joined by Reverend Michael Beckwith, founder of the Agape International Spiritual Center. They discuss spirituality, the power of thought, how we can help each other, and more. Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This show is sponsored by: OneSkin- Get 15% off OneSkin with the code MESSY at https://www.oneskin.co/ #oneskinpod Cionic- MeSsy listeners can get $50 off by entering the code MESSY during checkout. To learn more, visit cionic.com slash messy   Vuori- For our listeners, they are offering 20% off your FIRST purchase. Get yourself some of the most comfortable and versatile clothing on the planet at vuori.com/MESSY  Not only will you receive 20% off your first purchase, but enjoy free shipping on any U.S. orders over $75 and free returns.  BetterHelp- Stop comparing and start focusing, with BetterHelp. Visit BetterHelp.com/MESSY today to get 10% off your first month.
I Have MS... Google It

I Have MS... Google It

2024-07-1604:172

This week, Christina and Jamie discuss learning how to rest and slow down, being child actors, and more. Christina also shares some behind-the-scenes memories from hosting SNL. This episode was recorded in early 2024. Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: LMNT- Get your free LMNT Sample Pack with any purchase at DrinkLMNT.com/MESSY . Also try the new LMNT Sparkling — a bold, 16-ounce can of sparkling electrolyte water.” Lume- Control Body Odor ANYWHERE with @lumedeodorant and get 15% off with promo code MESSY at LumeDeodorant.com! #lumepod AG1- It’s easy and satisfying to start your journey with AG1. Try AG1 and get a FREE 1-year supply of Vitamin D3K2 AND 5 free AG1 Travel Packs with your first purchase at drinkAG1.com/messy.  Lolavie- Get 15% off LolaVie with the code [MESSY] at https://www.lolavie.com/messy  #lolaviepod
Will Ferrell

Will Ferrell

2024-07-0901:25:073

This week, on the 20th anniversary of “Anchorman,” Christina and Jamie are joined by Will Ferrell. They share memories from filming the movie and discuss how Will got into comedy, SNL, and more. Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This show is sponsored by: BetterHelp: This episode is sponsored by/brought to you by BetterHelp. Give online therapy a try at betterhelp.com/MESSY and get on your way to being your best self. Vuori: MeSsy listeners get 20% off your FIRST purchase. Get yourself some of the most comfortable and versatile clothing on the planet at vuori.com/MESSY and enjoy free shipping on any U.S. orders over $75 and free returns.  Babbel: Right now get up to 60% off your Babbel subscription - but only for our listeners - at Babbel.com/MESSY  Rules and restrictions may apply. Fatty15: Fatty15 is on a mission to replenish your C15 levels and restore your long-term health.  You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/messy and using code MESSY at checkout.
This week, Christina and Jamie discuss the ups and downs of living with a chronic illness, acceptance, the importance of paying attention to your body, and much more. This episode was recorded in early 2024. Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Cionic: MeSsy listeners can get $50 off by entering the code MESSY during checkout Visit cionic.com/messy  MudWtr: For a limited time, our listeners get up to 43% off your entire order, Free Shipping and a Free Rechargeable Frother when you use our exclusive link. Head to mudwtr.com/MESSY and grab your starter kit! ZocDoc: Go to Zocdoc.com/MESSY and download the Zocdoc app for FREE. Then find and book a top-rated doctor today. Jenni Kayne: Find your forever pieces @jennikayne and get 15% off with promo code MESSY15 at jennikayne.com/MESSY15! #jennikaynepartner
Sadie

Sadie

2024-06-2501:01:061

This week, Christina and Jamie are joined by a very special guest... Christina's daughter Sadie. She opens up about some of her own health challenges, what it's like to be the daughter of someone with MS, what it's like to be a thirteen year old right now, and much more. Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Vuori - Go to vuori.com/MESSY One Skin - For a limited time, you can try OneSkin for 15% off using the code MESSY at oneskin.co AG1 - drinkag1.com/messy
Sh*t Happens

Sh*t Happens

2024-06-1855:452

This week, Christina and Jamie discuss the importance of not holding things in, the stages of grief, finding people to lean on, and more. Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Cionic - MeSsy listeners can get $50 off by entering the code MESSY during checkout Visit cionic.com/messy  Honeylove - For a limited time only you can get Honeylove on sale. Get 20% Off your entire order with our exclusive link  honeylove.com/messy
Jennifer Esposito

Jennifer Esposito

2024-06-1101:05:021

This week, Christina and Jamie are joined by Jennifer Esposito. Jennifer opens up about her celiac disease and the struggle she went through to get a diagnosis. They also discuss the gaslighting of women, the importance of fighting for your health, her new film "Fresh Kills," and much more. Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This show is sponsored by: Vuori- Messy listeners get 20% off your FIRST purchase  at Vuori.com/MESSY and enjoy free shipping on any U.S. orders over $75 and free returns Fatty15- Fatty15 is on a mission to replenish your C15 levels and restore your long-term health.Get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com/MESSY and use code MESSY at checkout BetterHelp - Messy is sponsored by/brought to you by BetterHelp. Give online therapy a try at betterhelp.com/messy and get on your way to being your best self. Zoc Doc - Go to Zocdoc.com/MESSY and download the Zocdoc app for FREE. Then find and book a top-rated doctor today.
You Get What You Give

You Get What You Give

2024-06-0453:532

This week, Christina and Jamie discuss feeling trapped, missing high heels, their favorite shows that they’ve worked on, and more. This episode was recorded in early 2024. Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: AG1 - Try AG1 and get a FREE 1-year supply of Vitamin D3K2 AND 5 free AG1 Travel Packs with your first purchase at drinkAG1.com/messy. That’s drinkAG1.com/messy. Lume - New customers GET 15% ALL Lume products with code MESSY- and if you combine the 15% off with the already discounted starter pack, that equals over 40% off their Starter Pack! Use code MESSY for 15% off your first purchase at LumeDeodorant.com.  BetterHelp - Messy is sponsored by/brought to you by BetterHelp. Give online therapy a try at betterhelp.com/messy and get on your way to being your best self.
Katie Couric

Katie Couric

2024-05-2801:12:312

This week, Christina and Jamie are joined by Katie Couric. They discuss the importance of community and honesty, why we need more collaboration over competition, the changing media landscape, and more.  Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This show is sponsored by: Maybelline - If you, or someone you know is experiencing anxiety or depression, Maybelline New York is funding free, confidential support: Text TOGETHER to 741741 or visit Maybelline.com/bravetogether to learn more Lolavie -Get 15% off LolaVie with the code MESSY at https://www.lolavie.com/MESSY #lolaviepod  Cionic - MeSsy listeners can get $50 off by entering the code MESSY during checkout visit cionic.com
Jean Smart

Jean Smart

2024-05-2157:003

This week, Christina and Jamie are joined by Jean Smart. They share memories from when Christina and Jean worked together, and discuss taking back your power, embracing the quiet moments, her career trajectory, and much more. Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This show is sponsored by: Maybelline- If you, or someone you know is experiencing anxiety or depression, Maybelline New York is funding free, confidential support: Text TOGETHER to 741741 or visit Maybelline.com/bravetogether to learn more Vuori -Get 20% off your FIRST purchase of the most comfortable and versatile clothing on the planet at vuori.com/MESSY Zoc Doc - Go to Zocdoc.com/MESSY and download the Zocdoc app for FREE. Then find and book a top-rated doctor today.
Body Talk

Body Talk

2024-05-1455:575

This week, Christina and Jamie open up about their battles with eating disorders and self-esteem. They reflect on the moments that changed their lives, and discuss body dysmorphia, societal conditioning, how they each got to a healthier place, and more. *Trigger warning: discussion covers eating disorders and body image* Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Maybelline: If you, or someone you know is experiencing anxiety or depression, Maybelline New York is funding free, confidential support: Text TOGETHER to 741741 or visit Maybelline.com/bravetogether to learn more BetterHelp: This episode is sponsored by BetterHelp. Give online therapy a try at betterhelp.com/messy and get on your way to being your best self.” Cionic - MeSsy listeners can get $50 off by entering the code MESSY during checkout visit cionic.com
How Did You Know?

How Did You Know?

2024-05-0701:05:094

This week, Christina and Jamie discuss giving up control, feeling judgement, and Jamie shares how she knew to get tested for MS. They also answer some listener questions. Parts of this episode were recorded in 2023. Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Maybelline: If you, or someone you know is experiencing anxiety or depression, Maybelline New York is funding free, confidential support: Text TOGETHER to 741741 or visit Maybelline.com/bravetogether to learn more Lume: Control Body Odor ANYWHERE with @lumedeodorant and get 15% off with promo code messy at LumeDeodorant.com! #lumepod Vuori: For our listeners, they are offering 20% off your FIRST purchase. Get yourself some of the most comfortable and versatile clothing on the planet at vuori.com/MESSY BetterHelp: This episode is sponsored by BetterHelp. Give online therapy a try at betterhelp.com/messy and get on your way to being your best self.
Jimmy Kimmel

Jimmy Kimmel

2024-04-3053:152

This week, Christina and Jamie are joined by their friend, Jimmy Kimmel. They discuss finding humor in tough situations, the things he still wants to accomplish, speaking from your heart, mean tweets, and much more. Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This show is sponsored by: Maybelline - If you, or someone you know is experiencing anxiety or depression, Maybelline New York is funding free, confidential support: Text TOGETHER to 741741 or visit Maybelline.com/bravetogether to learn more Lolavie - Get 15% off LolaVie with code MESSY at https://www.lolavie.com/MESSY! #lolaviepod ZocDoc - Go to Zocdoc.com/MESSY and download the Zocdoc app for FREE. Then find and book a top-rated doctor today
Can I Be Honest?

Can I Be Honest?

2024-04-2348:571

This week, Christina and Jamie discuss feeling obligated to be strong, the importance of being there for each other, wearing diapers, and much more. They also answer some listener questions. Parts of this episode were recorded in 2023. Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by: Maybelline - If you, or someone you know is experiencing anxiety or depression, Maybelline New York is funding free, confidential support: Text TOGETHER to 741741 or visit Maybelline.com/bravetogether to learn more. Cionic - MeSsy listeners can get $50 off by entering the code MESSY during checkout visit cionic.com Jamie-Lynn Sigler is a paid spokesperson for Novartis. This podcast is independent from Jamie-Lynn Sigler’s collaboration with Novartis.
Martin Short

Martin Short

2024-04-1601:07:492

This week, Christina and Jamie are joined by Christina's friend, the one and only Martin Short. They reminisce about working together, share funny stories, discuss colonoscopy parties, and much more. Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick Audio Engineer: Josh Windisch This episode is sponsored by/brought to you by BetterHelp. Give online therapy a try at betterhelp.com/messy and get on your way to being your best self.
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Comments (18)

ID21798243

Christina and Jamie - Excellent job with the podcast. I really appreciate the honesty because it’s so hard to find in our world anymore especially in the media. I have a suggested topic for an upcoming episode. I would like to hear your thoughts around your changing self identity since having MS. I think this is one of the greatest struggles for everyone when there’s a sudden change to their life or their physical capabilities and no one seems to talk about the loss of one’s identity. Thx, Kat

Jul 7th
Reply (1)

Marta Connor

I have a Friend who has MS and is confined to a Wheel Chair. She can not find any Resources where she lives and desperately need help for her and her Daughter. My Name is Marta martaconnor@att.net Please Help!!!!

Jun 27th
Reply

April Potts

Magnesium oil spray with lavender and stuff helps me relax at night and sleep better through the pain.

May 26th
Reply

April Potts

I have to get tested for MS. The chronic pain is too bad and it’s not my arthritis or fibromyalgia. My rheumatologist says I need to see a neurologist so I’m waiting for the appointment. No matter what I do, the pain is always there. Microwave buttons make me feel like my wrist and fingers will break. The stabbing pain in my limbs feet and toes, hands and fingers and wrists. Very poor balance and I don’t feel the bottom of my feet too well numbness for years and face paralysis with headache.

May 26th
Reply

April Potts

I have to get tested for MS. The chronic pain is too bad and it’s not my arthritis or fibromyalgia. My rheumatologist says I need to see a neurologist so I’m waiting for the appointment. No matter what I do, the pain is always there. Microwave buttons make me feel like my wrist and fingers will break. The stabbing pain in my limbs feet and toes, hands and fingers and wrists. Very poor balance and I don’t feel the bottom of my feet too well numbness for years and face paralysis with headache.

May 26th
Reply

April Potts

My referral just got sent to the neurologist to begin the testing. Have symptoms going back since 20 and other tracers before that the pain is excruciating all the time. It doesn’t matter what I do. If I push the microwave button, I feel my wrist and finger will break. Pill bottles hurt to open sharp pains in my feet and toes, along with my hands and all the bones and joints in between. Migraines every day and blurry vision. My great aunt had it. I also have fibromyalgia and osteoarthritis.

May 26th
Reply

Martha Foreman Mostyn

I hàve to talk about your displeasure with Ozempic etc. you have an eating disorder. I am truly sorry for that but you have no idea those medicines are for many many people. I have been obese since I was in kindergarten. I would have never thought that for years but it is the truth. it has only been a few years that they have understood morbid obesity is genetic! Yep I finally find the reason for this lifelong problem in my 70s. i have so much more to say but limited character to use. Be kind.

May 15th
Reply

Jimmy Hopkins jr

love you ladies. I've have MS since 2019. You're show helps me a lot. letting me feel I'm not in this alone

May 14th
Reply

Kristina Mcclain

Hello... Christina talking about her poop issues, I can relate. I also have ulcerative colitis. Diapers are not fun,but I wanted to let you know that now having ms my poop problem has a mind of its own. When I got to go I GOT to go. I found these underwear from Esty, company name Pregzen who makes underwear "pretty" and easy to get off. They have "snaps" on the side for easy to get off. I found them after a issue in public with a poop accident & I had clean myself up. Never again! Hope it helps

Apr 25th
Reply

Jamie Curci Carter

I totally get you both, and if you never have any other jobs, the podcast is enough.

Apr 5th
Reply

Kristina Mcclain

Hi MS crew, Christina I love hearing from someone that is in the same boat and feeling as I am. I was diagnosed in 2022 and it came on very quickly for me. I had 22 systoms at the time. I ulcerative colitis also and the medicine I was on for uc bought out the ms. I want to thank you for coming out publicly when you did cuz it made me not feel alone or crazy. This podcast has helped make me feel like I am not alone (lol there's times I am finishing your sentences or saying the same thing). Tks

Apr 4th
Reply

Michelle Downey

what type of treatment do you both do? if you don't mind me asking. I'm on ocrevus infusion

Apr 2nd
Reply

Michelle Downey

you guys got me crying talking about kids. I'm struggling not being super mom since my diagnosis and struggling to show them or tell them about what I'm having problems with

Apr 2nd
Reply

Michelle Downey

so happy to have found this pod cast, I'm literally in the same boat trying to stay a float as you Christina! I'm on year two of being diagnosed with MS and still in that feeling shitty stage and definitely in the eff off stage of MS. I'm struggling figuring out the new me and "new" mom with MS, I say new bc I really feel like I'm starting over bc I'm so different then I've ever been as a mom. what kind of mom am I now, besides so fucking tired!

Mar 29th
Reply (2)

selena

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Mar 16th
Reply