Medicine 3.0

Join host Dr. Catherine Isaac as she speaks with orthopedic surgeon and sports medicine specialist Dr. Jocelyn Wittstein about the often overlooked musculoskeletal impacts of menopause. Learn how declining estrogen levels affect joints, bones, and muscles, contributing to conditions like frozen shoulder (which predominantly affects women aged 40-60), accelerated arthritis, and faster bone density loss. Dr. Wittstein shares treatment approaches, the importance of strength training during menopause, and lifestyle modifications to support musculoskeletal health. Whether you're experiencing unexplained joint pain or want to be proactive about your bone health, this episode provides valuable insights into managing this under-discussed aspect of menopause.

In this enlightening conversation, Bionic Health's Dr. Jared Pelo sits down with Dr. William Evans, Professor of Human Nutrition at UC Berkeley and pioneering researcher in the field of sarcopenia (age-related muscle loss).What You'll Learn:Why muscle mass might be the most important predictor of healthy agingThe revolutionary D3 creatine dilution method that accurately measures functional muscle massHow much muscle is needed to maintain mobility as we ageThe strong connection between muscle mass and cognitive functionPractical strategies to maintain and build muscle at any ageDr. Evans shares groundbreaking research showing that muscle is truly "the currency of aging," affecting everything from mobility and fall risk to cognitive function and insulin sensitivity. Discover why resistance training is effective even for 90-year-olds and why adequate protein intake becomes increasingly important as we age.This conversation offers valuable insights for anyone looking to optimize their health through evidence-based approaches to muscle maintenance - a key factor in Bionic Health's mission to enable optimal health for all.🔍 About Dr. William Evans: Professor of Human Nutrition at University of California Berkeley with an adjunct appointment at Duke University's geriatrics program. Dr. Evans coined the term "sarcopenia" and has been at the forefront of research into age-related muscle loss for decades.📱 Follow Bionic Health: Website: https://bionichealth.com Instagram: @bionichealth Twitter: @bionichealth#OptimalHealth #HealthyAging #Sarcopenia #MuscleHealth #PreventativeMedicine #BionicHealth

Join Bionic Health advisors Kelly and Anna as they break down the science and benefits of comprehensive performance testing. Whether you're a fitness enthusiast or just beginning your health journey, discover how establishing baseline measurements across multiple fitness domains can transform your approach to exercise.In this episode, learn about:- The complete performance testing protocol at Bionic Health- How VO2 Max testing measures your cardiovascular fitness- Strength and mobility assessments that predict healthy aging- Why power testing matters (and what your vertical jump reveals!)- How often you should retest to track meaningful progress"There's really no pressure to get any certain score right off the bat. It's just getting more information that's valuable for how to improve looking forward." - Anna, Bionic Health AdvisorReady to establish your fitness baseline? Contact your Bionic Health advisor today to schedule your performance testing session.

Join Dr. Jared Pelo as he interviews cardiologist Dr. Mike McConnell about revolutionizing our approach to heart disease. Dr. McConnell shares insights from his book "Fight Heart Disease Like Cancer," explaining why we should detect and treat cardiovascular disease early, just as we do with cancer. Learn about cutting-edge screening tools including coronary calcium scans, retinal imaging with AI, and CT angiograms. Discover how technology and lifestyle modifications can help prevent heart attacks and strokes before they happen. As a Stanford cardiologist and former Google researcher, Dr. McConnell brings unique expertise in both clinical practice and health technology innovation. This conversation could save your life or the life of someone you love. 

Join Catherine Isaac as she interviews Alex Ladan, a former gymnast and current Bionic Health member, who shares her journey from competitive athletics to personalized health optimization. Alex reveals how working with her Bionic Advisor has helped her manage stress, improve nutrition, establish better morning routines, and approach her upcoming wedding with a healthy mindset. Learn how regular check-ins, accountability, and collaborative goal-setting have transformed Alex's energy levels and daily habits. Whether you're an athlete, health professional, or someone looking to optimize your wellness routine, this conversation offers valuable insights into how personalized health coaching can help identify barriers, create sustainable habits, and develop a holistic approach to health beyond traditional healthcare.

Join Kelly Joniak and Dr. Catherine Isaac as they delve into the comprehensive sleep module from Bionic Health. In this insightful episode, Dr. Isaac explains the multifaceted approach to improving sleep quality, including sleep diary analysis, wearable data integration, hormone testing, and practical lifestyle modifications.Discover how cortisol patterns affect sleep, learn about chronotypes and their impact on your daily rhythm, understand the truth about melatonin supplements, and explore the evidence behind popular sleep aids. Dr. Isaac shares expert recommendations on caffeine timing, supplements like magnesium threonate and ashwagandha, and offers perspective on how to interpret your sleep data without letting it dictate how you feel.Whether you're struggling with sleep or simply looking to optimize your rest, this episode provides science-backed strategies to help you achieve better sleep quality and overall health.#Sleep #BiometricHealth #SleepScience #WellnessJourney #HealthOptimization

In this episode, we sit down with Dr. Christin Glorioso, physician, neuroscientist, and founder of NeuroAge, to discuss the cutting-edge science behind brain aging and Alzheimer's prevention.Dr. Glorioso shares her personal journey from witnessing her grandmother's battle with Alzheimer's to discovering her own genetic predisposition to the disease. Learn how this motivated her to dedicate her career to developing solutions for those at high risk of dementia.The science behind brain aging and its connection to dementiaHow being "biologically 5 years younger" can protect against Alzheimer'sThe 6 key lifestyle factors that can reduce your risk by up to 40%Revolutionary testing methods using transcriptomics, brain MRIs, and cognitive assessmentNeuroAge's mission to develop "a statin for Alzheimer's"Dr. Glorioso explains how her 20 years of research on human brain aging has led to groundbreaking insights about preventing cognitive decline. She discusses how lifestyle changes can mitigate genetic risks and shares specific recommendations for maintaining brain health.Whether you're concerned about your own cognitive future or that of a loved one, this episode offers hope and practical advice for preserving brain function as we age.#BrainHealth #AlzheimersPrevention #Neuroscience #Dementia #HealthTech #Longevity

In this episode of Medicine 3.0, Bionic Health physician Dr. Catherine Isaac sits down with Bionic advisor Kelly Joniak to explore the Body Composition Module—one of the most informative tools available to Bionic Health members.Join them as they break down:The science behind DXA scans and how they provide a comprehensive three-compartment model of your body (bone, fat, and muscle)Why understanding visceral fat is crucial for assessing disease risk beyond what typical scales can measureHow body composition analysis helps identify hidden health risks like potential osteoporosis and fatty liverThe difference between various body composition measurement tools (DXA, bioimpedance scales, skin fold testing)Practical recommendations for building muscle mass, reducing visceral fat, and improving overall healthWhether you're looking to optimize your health journey or simply curious about the science behind body composition, this conversation offers expert insights that go far beyond the numbers on your bathroom scale.Follow Bionic Health for more episodes of Medicine 3.0, where cutting-edge healthcare meets practical wisdom for optimal health and longevity.

Join Dr. Jared Pelo as he interviews neurologist-turned-entrepreneur Dr. Josh Turknett about his journey from clinical practice to founding BrainJo, a platform that uses neuroscience principles to teach musical instruments. Learn how complex skills like music can help maintain cognitive health, and discover practical strategies to stimulate your brain and prevent cognitive decline as you age.Timestamps:00:01 - Introduction and welcome00:13 - Josh's background and journey from neurologist to entrepreneur02:59 - Josh's personal experience with migraines and lifestyle changes03:59 - Discovering neuroplasticity and challenging fixed mindsets about adult learning06:51 - Transitioning from clinical neurology to broader impact10:09 - The challenge of leaving clinical practice and finding new ways to help people11:40 - How BrainJo evolved to address cognitive health14:33 - Musical instruments you can learn at BrainJo (banjo, piano, ukulele, fiddle)15:26 - Assessing cognitive decline risk and preventative strategies17:39 - The importance of monitoring cognitive function18:37 - Key nutrients for brain health (B12, vitamin D, magnesium, zinc, copper)20:33 - Why genetics isn't deterministic for cognitive decline21:29 - The value of cognitive testing and brain games23:27 - Practical advice for a 45-year-old to prevent cognitive decline24:03 - The "stimulate and support" framework for brain health29:19 - What types of physical activity are best for brain health33:08 - The surprising importance of social connection for brain health36:46 - Josh's new book "Anyone Can Play Music" and the science of learning40:31 - Conclusion and where to find more informationAbout Dr. Josh TurknettNeurologist by training, Dr. Turknett transitioned from clinical practice to found BrainJo, which integrates neuroscience principles into music instruction. His approach helps people realize their musical potential while maintaining cognitive health throughout their lives.Check out Josh's new book "Anyone Can Play Music: How to Realize Your Musical Potential with the Laws of BrainJo" wherever books are sold.Learn more at brainjo.academy#BionicHealth #BrainHealth #Neuroscience #MusicLearning #CognitiveDevelopment #Neuroplasticity

In this informative episode of Medicine 3.0, host Catherine Isaac welcomes back dermatologist Dr. Jennifer Goldwasser to discuss aging skin and rejuvenation techniques. This comprehensive conversation covers everything from understanding the natural aging process of skin to practical advice on skincare routines and treatments. Dr. Goldwasser shares her expert insights on effective over-the-counter products, prescription options, and cosmetic procedures, while emphasizing a "subtraction first" approach to skincare that focuses on removing harmful factors before adding treatments.Learn about the effects of sun exposure on aging skin, how to select appropriate moisturizers for your skin type, the benefits and proper application of retinoids, and when to consider treatments like Botox, fillers, or laser therapy. Dr. Goldwasser also addresses common skin conditions like seborrheic dermatitis and melasma, while offering practical advice for maintaining healthy skin throughout the aging process.Timestamps:00:00 - Introduction02:39 - Effects of sun exposure on skin aging05:39 - The subtraction approach to skincare09:01 - Gentle cleansers and proper product selection11:57 - Understanding seborrheic dermatitis16:57 - Menopause and skin changes23:36 - Types of moisturizers and proper application32:21 - Effective skincare ingredients37:14 - Anti-aging ingredients: retinols and vitamin C44:21 - How to properly apply tretinoin53:13 - Benefits of tretinoin for aging skin57:44 - Botox, fillers and other cosmetic procedures1:04:36 - Innovative treatments in dermatology1:12:27 - Conclusion and preview of future episodes

Join Bionic Health Advisors Kelly Joniak and Anna Simmons as they share practical nutrition strategies, meal prepping techniques, and how to make healthy eating more manageable in our busy lives. Learn the difference between meal prep and batch cooking, how to optimize your food environment, and get actionable tips for grocery shopping and maintaining consistency despite busy schedules.In this episode, discover how strategic protein distribution, time-saving food prep techniques, and environmental design can transform your nutrition habits without relying on willpower alone. Whether you're a nutrition newbie or looking to level up your meal game, this episode delivers practical strategies you can implement today!TIMESTAMPS:00:01 - Introduction to Anna Simmons01:40 - Anna's experience as a Bionic member and advisor03:20 - Meal prep vs. batch prep: What's the difference?05:55 - Pros and cons of different meal preparation approaches10:05 - Food environment optimization strategies12:43 - Nutrition recommendations and assessment process19:52 - Grocery shopping strategies and planning24:39 - Understanding non-linear progress in nutrition27:20 - Solutions for busy schedules31:57 - Final thoughts and beginner advice#MealPrep #NutritionTips #HealthyEating #FoodPrep #ProteinDistribution #HealthyHabits #MealPrepSunday #BionicHealth #Medicine3Point0

Join Kelly Joniak, Bionic Advisor, and Dr. Catherine Isaac, Physician at Bionic Health, as they dive deep into the Vascular Module offered to Bionic Health members. Learn about the comprehensive approach to cardiovascular health assessment, from baseline evaluations to specialized testing that goes beyond traditional medical care.In this episode, Dr. Isaac explains:How Bionic identifies members who would benefit from the vascular moduleKey biomarkers like lipid panels, ApoB, lipoprotein(a), and inflammatory markersThe role of coronary artery calcium scoring in assessing plaque buildupPersonalized approaches to treatment based on cholesterol balance testingEvidence-based lifestyle modifications including the 800-gram dietWhen medications like statins are appropriate and how they're personalizedDiscover how Bionic Health takes a proactive approach to cardiovascular health rather than the reactive model of traditional medicine, helping members address potential issues years before they might become clinical problems.#BionicHealth #PreventiveMedicine #CardiovascularHealth #Longevity #HealthcareInnovationKey Timestamps:00:00 - Introduction and welcome with Kelly Joniak and Dr. Catherine Isaac00:46 - Overview of the vascular module and baseline evaluation03:05 - Explanation of lipid panel testing (cholesterol, triglycerides, HDL, LDL)04:25 - Deep dive on Apolipoprotein B (ApoB) and its significance05:32 - Lipoprotein(a) explained and how it affects plaque buildup07:30 - Discussion on lab work timing and what blood tests actually show09:59 - Coronary artery calcium scoring and how it works12:32 - Explanation of plaque formation and calcification process15:16 - Lifestyle recommendations based on risk factors17:37 - When medications are appropriate for higher-risk patients19:59 - Cholesterol balance testing and personalized treatment approaches21:29 - Addressing myths about statin medications23:04 - Inflammatory markers and their role in cardiovascular assessment25:21 - Omega-3 index testing and supplement recommendations27:36 - The importance of lifestyle fundamentals over supplements alone30:06 - Closing thoughts on proactive vs. reactive healthcare approaches

Join Dr. Catherine Isaac and Kelly Joniak as they explore Bionic Health's female hormone module. Learn about hormone testing and treatment options for premenopausal, perimenopausal, and postmenopausal stages. Dr. Isaac explains when hormone testing is beneficial, who's an ideal candidate for hormone replacement therapy, and what lifestyle modifications can support optimal health during hormonal transitions. Discover the pros and cons of treatment and how Bionic Health's personalized approach helps women make informed decisions about their health.Timestamps:00:00 - Introduction and welcome00:25 - Defining the female hormone module01:42 - Explaining pre-menopausal, peri-menopausal, and post-menopausal stages03:38 - Who benefits most from the female hormone module03:52 - Limitations of hormone testing during birth control use06:14 - Conditions monitored in pre-menopausal patients (hypothalamic amenorrhea, PCOS)08:43 - Symptoms of perimenopause and diagnostic challenges09:52 - Bionic Health's approach to treatment12:12 - Indications for hormone therapy (early menopause, genitourinary symptoms)14:16 - Benefits of hormone replacement therapy16:43 - Weight changes during perimenopause and lifestyle recommendations19:33 - Exercise recommendations during hormonal transitions24:16 - Timing considerations for hormone therapy implementation26:41 - Risks associated with hormone therapy (breast cancer, blood clotting)29:02 - Progesterone's role and potential side effects32:03 - Closing thoughts on Bionic's personalized approach

In this episode, Dr. Jared Pelo sits down with Amber Brueseke, founder of Biceps After Babies, to discuss her journey from nurse to fitness coach and how she's helped over 10,000 women transform their relationship with fitness and nutrition. Amber shares how her early exposure to weightlifting through her mom shaped her path, her discovery of macro counting, and her evolution as a coach. Key topics include: The importance of being a positive fitness role model for the next generation Understanding the science and psychology behind self-sabotaging behaviors How reverse dieting works and why it's crucial for long-term success Using macro counting as a bridge to sustainable, moderate eating habits The role of beliefs, values, and identity in creating lasting change Connect with Amber: Instagram/TikTok/Facebook: @biceps.after.babies Website: bicepsafterbabies.com Podcast: Biceps After Babies Radio Key Timestamps 00:00 - Introduction to Amber Brueseke 00:40 - Amber's fitness journey starting at age 14 01:55 - Transitioning from nursing to fitness instruction 04:20 - Discovery of macro counting and getting a six pack 05:45 - Building Biceps After Babies and serving 10,000+ women 07:28 - Breaking negative generational patterns around fitness 09:14 - Being a fitness role model at any age 10:35 - Evolution as a coach and understanding behavior change 14:19 - Understanding self-sabotaging behaviors 16:24 - The "tree framework": beliefs, values, and identity 21:27 - Explaining reverse dieting and metabolic adaptation 27:57 - Why cycling between deficit and maintenance is crucial 30:12 - Using macro counting as a bridge to moderation 32:14 - Building sustainable nutritional awareness 34:30 - Where to find Amber and Biceps After Babies

A conversation with entrepreneur and attorney Andrew Fisher about his transformation from a sedentary lifestyle to achieving his best health in his 40s through CrossFit, hormone optimization, and embracing modern medicine. In this episode, Andrew shares his journey from being a multi-sport athlete in his youth to struggling with weight in college and law school, and eventually finding his path back to fitness through running, yoga, and CrossFit. He discusses how seeing his parents' health challenges motivated him to take control of his own health, and how modern interventions like GLP-1s and hormone optimization helped him achieve remarkable results - including gaining 8 pounds of muscle while losing 40 pounds overall. 🕒 Timeline: 00:00 - Introduction and background 00:48 - Early years and education 02:42 - Sports background and high school athletics 04:50 - Health challenges during college and law school years 06:48 - Getting back into fitness through running and P90X 08:42 - Discovering and committing to CrossFit 12:10 - The community aspect of CrossFit 13:36 - Family health history and motivation 17:25 - Early attempts at weight loss and dieting 21:57 - Finding Bionic Health and comprehensive health optimization 24:14 - Results from hormone optimization and GLP-1 medication 28:55 - Mental freedom from food obsession 31:00 - The importance of medical supervision and evidence-based interventions #BionicHealth #HealthOptimization #Fitness #Wellness #CrossFit #HealthyAging

Join Dr. Catherine Isaac as she sits down with Dr. Jennifer Goldwasser, a board-certified dermatologist with over 30 years of experience, as she shares expert insights on skin cancer prevention, detection, and treatment. Learn about different types of skin cancer, risk factors, the importance of early detection, and practical prevention strategies including proper sunscreen use. Perfect for healthcare professionals and anyone interested in protecting their skin health.  Key Timestamps:   0:00 Introduction   0:53 Types of skin cancer explained   3:29 Advances in melanoma treatment   4:16 Importance of immune system health   5:16 Impact of non-melanoma skin cancers   8:57 Risk factors and genetic connections   11:02 Common locations for different skin cancers   14:30 High-risk patient screening   21:44 Amelanotic melanoma in redheads   26:15 Skin cancer in people of color   31:01 Physical examination tips   40:09 ABCDE prevention strategy   42:07 Sunblock types and proper usage   49:24 Sunscreen product recommendations   54:00 Daily sun protection guidance  #SkinCancer #Dermatology #SkinHealth #MedicalEducation #Prevention #Healthcare #Sunscreen 

Join Dr. Jared Pelo and Shalin Shah for an in-depth discussion about revolutionizing testosterone therapy. Shah, with his extensive background in healthcare investment and drug development, shares insights about Kyzatrex, an innovative oral testosterone medication, and discusses why testosterone has been misunderstood in medicine.    Learn about:  Why testosterone was historically vilified and how recent research is changing perspectives  The groundbreaking Traverse Study and its implications for cardiovascular health  How daily oral testosterone better mimics the body's natural rhythm compared to injections  The critical role of testosterone in metabolic health, diabetes prevention, and longevity  Why testosterone testing should be standard in preventive care  The future of hormone therapy for both men and women    Key Timestamps:   00:18 - Shalin's journey into testosterone research and development of Kyzatrex  03:18 - Understanding oral testosterone and debunking liver toxicity myths  06:03 - Historical misconceptions: Why testosterone was unfairly vilified  11:04 - The Traverse Study (2023): Proving cardiovascular safety  13:28 - T4DM Study: Testosterone's impact on diabetes prevention  15:22 - Why daily oral testosterone better mimics natural body rhythms  24:05 - The Testosterone Project's three initiatives:  - Making testosterone testing standard  - Creating FDA-approved options for women  - De-scheduling testosterone  36:09 - Why Kyzatrex chose a cash-pay model for better access    Featured Links:   Learn more about Kyzatrex: https://www.kyzatrex.com/  Educational resources: https://www.rethinktestosterone.com  Testosterone Project: https://testosteroneproject.com    #HormoneHealth #Testosterone #Healthcare #WellnessPodcast #MedicalInnovation #HealthOptimization 

In this episode of the Bionic Health Podcast, Dr. Jared Pelo sits down with Scott, a tech executive and health optimization pioneer, to discuss his remarkable journey toward optimal health. Scott shares how he transformed his approach to fitness and nutrition, proving that small, consistent changes can lead to extraordinary results.    Key moments:  0:00 - Introduction and background  3:26 - The reality of aging and discovering swimming  6:18 - The importance of healthspan vs. lifespan  11:16 - Beginning the health optimization journey  15:32 - Dealing with comprehensive blood work results  22:44 - Major health transformations and wins  27:17 - Insights on nutrition and sustainable lifestyle changes    Highlights from the conversation:    How Scott taught himself to swim using a book  The impact of understanding health data and biomarkers  Transforming body composition through strength training  The power of gradual, systematic changes over quick fixes  Practical approaches to nutrition and portion control    Follow Bionic Health:  Website: bionichealth.com  Instagram: @bionichealth  Twitter: @bionichealth  #HealthOptimization #Longevity #Wellness #BionicHealth #HealthSpan #PreventiveMedicine 

Join Dr. Jared Pelo as he sits down with sport scientists Dr. Morgan Smith and Dr. Mo Merritt to explore the fascinating intersection of human performance, mindset, and metrics. Dr. Smith, a postdoctoral researcher at Stanford studying applied human performance, and Dr. Merritt, who works with the United States Olympic and Paralympic Committee, share their unique perspectives on athletic development and achievement.  In this enlightening conversation, discover:  How metrics and data can both help and hinder athletic performance  The importance of developing a growth mindset when learning new skills  Why the "coach's eye" remains crucial in an age of advanced metrics  Practical strategies for pushing past perceived limitations  The value of embracing discomfort in the pursuit of growth  Whether you're an athlete, coach, or someone interested in optimizing your performance, this discussion offers valuable insights into the delicate balance between objective metrics and subjective experience. Learn why checking in with yourself before checking your metrics might be the key to sustainable progress, and why enjoying the process - or as Dwyane Wade puts it, "enjoying the traffic" - could be more valuable than focusing solely on outcomes.     0:00 - Introduction and Guest Backgrounds   2:26 - Morgan Smith's Path to Sport Science   3:05 - Mo Merritt's Journey Through Kinesiology and Team USA  6:58 - Applied Sports Science and Performance Research   9:16 - Working with Athletes and Real-Time Data Collection   12:18 - Learning New Skills and Brain Aging   14:02 - Practical Mindset Strategies for Athletes   15:03 - Acceptance and Different Approaches to Mental Challenges   18:20 - Managing Performance Metrics and Self-Assessment   20:09 - Performance Beyond Readiness Scores   21:34 - Tools vs. Metrics: Finding the Right Balance   24:39 - Using Metrics to Push Past Barriers   27:19 - Understanding Physical Capacity and Effort   29:20 - Building Trust and Taking First Steps   31:45 - Key Takeaways:  Morgan: Finding Enjoyable Movement and Self-Kindness  Mo: "Enjoying the Traffic" - Embracing the Process   34:55 - Closing and Contact Information    Connect with Dr. Morgan Smith and Mo Merritt to explore more about their work in health and longevity. Don't forget to like, subscribe, and share for more insights on optimizing your well-being! #HumanPerformance #SportScience #Athletics #Mindset #Performance #Coaching #Sports #Olympics 

Dr. Jared Pelo speaks with Mike Rucker, author of "The Fun Habit," about moving beyond toxic positivity and finding sustainable ways to incorporate enjoyment into daily life. Learn how intentional fun can improve mental health, work performance, and overall wellbeing. Key Timestamps: 0:00 - Introduction and Mike's background 2:37 - Personal story of loss and realizing the problems with toxic positivity 4:32 - The science of hedonic tone and the difference between fun and happiness 9:13 - Discussing grief and finding joy during difficult times 14:29 - How to analyze and improve how you spend your time 17:46 - Research on pleasure-seeking behavior and the "fun cup" concept 21:23 - Understanding hedonic tone and valence 24:07 - Practical tools for adding fun to everyday life 29:14 - Transition rituals between work and home life 34:21 - The concept of "healthy hedonism" and behavior change 40:07 - Making health interventions enjoyable and sustainable 45:51 - Personal stories about finding enjoyment in exercise 51:54 - Where to find Mike and his book "The Fun Habit" Connect with Mike Rucker: Instagram: @thewonderoffun Website: https://michaelrucker.com/ To Purchase The Fun Habit: https://www.amazon.com/gp/product/1982159057 #Psychology #MentalHealth #Wellness #PersonalDevelopment #Fun #PositivePsychology