NBC Nightly News with Lester Holt

Biden diagnosed with ‘aggressive’ form of prostate cancer; 2 dead, more than a dozen injured after Mexican navy ship crashes into Brooklyn Bridge; FBI calls California fertility clinic bombing an ‘act of terrorism’; and more on tonight’s broadcast.

Urgent manhunt for Louisiana escaped inmates; Devastating tornado hits St. Louis; Commuter chaos as NJ Transit engineers go on strike; and more on tonight’s broadcast.

In this bonus episode of The Drink, Kate Snow sits down with Oscar-winning actor Da’Vine Joy Randolph, who is celebrated for her standout performance in “The Holdovers.” Randolph opens up about her unexpected path to acting — how she once aspired to be an opera singer, only to be steered in a different direction after a surprising setback. She reflects on the pivotal moments that shaped her career, from her Broadway breakthrough to the exciting new projects she’s taking on today.

Justices hear arguments in birthright citizenship case; Cassie Ventura cross-examined in Sean ‘Diddy’ Combs’s trial; Air traffic control outage in critical Denver airport hub; and more on tonight’s broadcast.

Cassie Ventura testifies about physical abuse and rape at Diddy trial; Trump in Qatar on high-stakes Mideast trip; Dangerous early heat wave scorches Texas; and more on tonight’s broadcast.

Sean ‘Diddy’ Combs’ ex-girlfriend Cassie Ventura gives bombshell testimony; Menendez brothers resentenced to 50 years to life with parole; Trump kicks off high-stakes mideast trip in Saudi Arabia; and more on tonight’s broadcast.

Stocks surge after U.S. and China announce pause on most tariffs; Lester Holt speaks with Pope Leo; U.S. hostage Edan Alexander released; and more on tonight’s broadcast.

Hamas says it will release last living American hostage in Gaza; New air traffic control outages in Newark and Atlanta; New questions on White House's deal with China; and more on tonight’s broadcast.

Pope Leo XIV makes surprise appearances on Saturday; 4.1 earthquake rocks southern states; U.S. China negotiators meet in Switzerland for trade talks; and more on tonight’s broadcast.

American cardinals reveal what led to the election of Pope Leo XIV; Tracing Pope Leo XIV’s roots in South America; Another radar outage for Newark Air Traffic Controllers; and more on tonight’s broadcast.

Leo XIV elected as first American pope; U.S. and U.K. announce new trade agreement; New air traffic control overhaul plans detailed; and more on tonight's broadcast. 

Black smoke signals no new pope chosen on first day of conclave; Three ex-Memphis police officers found not guilty in death of Tyre Nichols; New protests break out at Columbia University; and more on tonight’s broadcast.

Source: Newark ATC communications blackout happened twice before; President Trump meets Canada’s new leader amid trade war; Lawsuit seeking $50 million accuses Smokey Robinson of rape; and more on tonight’s broadcast.

Trump launches incentives for migrants in the U.S. illegally to ‘self deport’; Search underway after suspected smuggling boat capsizes near San Diego; Dave Portnoy speaks out after antisemitic incident at Barstool bar; and more on tonight’s broadcast.

Exclusive: Trump defends second term agenda in new interview; Warren Buffett sounds alarm on trade war; Air traffic controller shortage leads to delays at major travel hub; and more on tonight’s broadcast.

Nearby military chopper causes planes to abort landings at Reagan Airport; Strong jobs report amid tariff uncertainty; TEMU halting shipments from China to U.S. customers; and more on tonight’s broadcast.

Trump removes Waltz as national security advisor in first major shake-up; Massive delays at one of the busiest airports in the U.S.; Businesses small and large warn about impacts of trade war; and more on tonight’s broadcast. 

Trump blames Biden for 0.3% decline in GDP;U.S. ports bracing for big drop in shipping; Judge orders release of Columbia student Mohsen Mahdawi; and more on tonight’s broadcast.

Trump marks 100 days of second term at Michigan rally; Trump announces changes to auto tariffs; Severe weather wreaks havoc in southern Missouri; and more on tonight’s broadcast.

Trump administration touts border security as 100-day mark nears; Inside El Salvador prison holding deported migrant; Millions without power following European blackout; and more on tonight’s broadcast.