DiscoverThe Curbsiders Internal Medicine Podcast#487 Chronic Pain & Opioid Use Disorder with Dr. Jessie Merlin
#487 Chronic Pain & Opioid Use Disorder with Dr. Jessie Merlin

#487 Chronic Pain & Opioid Use Disorder with Dr. Jessie Merlin

Update: 2025-06-161
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This podcast features an interview with Dr. Morelin on managing chronic pain in patients with opioid use disorder (OUD). The discussion highlights the reciprocal relationship between pain and addiction, emphasizing the need to address both simultaneously. Common clinical misconceptions and mistakes are addressed, including the importance of avoiding stigmatizing language and recognizing the co-occurrence of both conditions. The podcast details assessment strategies, including functional assessments (PEG), pain history, and substance use history, stressing the need for a patient-centered approach and building trust. Effective interventions discussed include buprenorphine and methadone for OUD and pain management, along with behavioral therapies like CBT and pain self-management programs. The role of FDA-approved medications (buprenorphine, methadone, naltrexone) is explored, including their advantages, disadvantages, and regulatory aspects. The podcast also provides practical tips for goal setting, patient communication, and integrating non-pharmacologic interventions into clinical practice, including utilizing interdisciplinary team members and local resources. Finally, the complex decision-making process involved in restarting opioids is discussed, emphasizing a comprehensive approach and thorough risk-benefit assessment. A case study of a 55-year-old man with chronic pain, diabetes, and a history of OUD further illustrates these concepts.

Outlines

00:00:44
Understanding Chronic Pain and Opioid Use Disorder

This section introduces the reciprocal relationship between chronic pain and opioid use disorder, highlighting common misconceptions and the importance of integrated treatment approaches.

00:10:00
Case Study and Treatment Options

A case study illustrates the complexities of managing chronic pain and OUD, showcasing the assessment process and various treatment options, including buprenorphine and methadone.

00:19:06
Avoiding Clinical Errors in Management

This section focuses on common mistakes clinicians make when managing patients with chronic pain and OUD, emphasizing the importance of patient-centered care and avoiding stigmatizing language.

00:22:42
Comprehensive Assessment and Treatment Strategies

Details the assessment process, including functional assessments, pain and substance use history, and the importance of addressing trauma and fragmented care. Emphasizes patient-centered care and building trust.

00:29:48
Medication Management: Buprenorphine and Methadone

This section focuses on the use of buprenorphine and methadone for chronic pain and OUD, highlighting research limitations and the need for flexible approaches.

00:36:18
Medications for Opioid Use Disorder (MOUD) and Regulations

Provides an overview of FDA-approved medications for OUD (buprenorphine, methadone, naltrexone), discussing their advantages, disadvantages, and regulatory aspects.

00:41:57
Non-Pharmacologic Pain Management Strategies

Explores effective behavioral interventions like CBT and pain self-management programs, and strategies for integrating these approaches into clinical practice.

00:52:29
Goal Setting, Patient Communication, and Restarting Opioids

This section covers practical tips for goal setting, patient communication, and the clinical considerations involved in restarting opioids for patients with chronic pain and OUD.

Keywords

Chronic Pain


Pain lasting ≥3 months beyond normal tissue healing. Impacts 20% of US population, 6% severely. Often intertwined with addiction.

Opioid Use Disorder (OUD)


A chronic relapsing brain disease characterized by compulsive drug seeking and use despite harmful consequences. Often co-occurs with chronic pain.

Buprenorphine


An opioid partial agonist used to treat OUD and chronic pain. Available in various formulations, with ongoing research exploring optimal dosing for pain management.

Methadone


A full opioid agonist used to treat OUD. Often administered in specialized clinics, with limitations in flexibility and split-dosing compared to buprenorphine.

Cognitive Behavioral Therapy (CBT)


A type of psychotherapy that helps individuals identify and change negative thinking patterns and behaviors contributing to chronic pain.

Pain Self-Management Programs


Manualized CBT programs focusing on behavioral strategies to improve pain self-efficacy and function. Adaptable for various populations, including those with OUD.

Reciprocal Model of Pain and Addiction


A model illustrating the bidirectional relationship between pain and substance use.

Patient-Centered Care


A healthcare approach that prioritizes the patient's needs, preferences, and values in all aspects of care.

Methadone Treatment Programs


Specialized clinics that administer methadone for OUD treatment.

Q&A

  • What is the reciprocal model of pain and addiction, and how does it impact clinical management?

    The reciprocal model highlights the bidirectional relationship between pain and addiction. Pain can drive substance use, while addiction can worsen pain. Clinicians must address both simultaneously.

  • What are some common mistakes clinicians make when managing patients with chronic pain and OUD?

    Common mistakes include failing to recognize the co-occurrence of both conditions, focusing solely on one condition, using stigmatizing language, and not adequately assessing the patient's functional status and priorities.

  • What non-pharmacologic interventions are effective for chronic pain in patients with OUD?

    Cognitive Behavioral Therapy (CBT), pain self-management programs, and mindfulness-based interventions are evidence-based approaches.

  • How should clinicians approach the decision to restart opioids in patients with chronic pain and OUD?

    The decision should be based on a careful risk-benefit assessment, considering the patient's individual risk factors, prognosis, and available alternatives. Buprenorphine is often a safer first-line opioid choice.

  • What are some practical tips for integrating chronic pain management strategies into primary care?

    Utilize available local resources, educate patients on self-management strategies, and consider a multidisciplinary approach. Document observations clearly and avoid stigmatizing language.

Show Notes

Dive into practical, evidence-based approaches to managing pain in patients with opioid use disorder, bust common myths, and explore strategies to support patients. This episode will enhance your skills in providing holistic, patient-centered care. We’re joined by Dr. Jessica Merlin, @JessicaMerlinMD (University of Pittsburgh). 



Claim CME for this episode at curbsiders.vcuhealth.org!

By listening to this episode and completing CME, this can be used to count towards the new DEA 8-hr requirement on substance use disorders education.



Episodes | Subscribe | Spotify | iTunes | CurbsidersAddictionMed@gmail.com | CME!



Credits






  • Producer, Show Notes, Infographics: Carolyn Chan MD, MHS

  • Hosts: Carolyn Chan, MD, MHS and Shawn Cohen MD

  • Reviewer: Payel Jhoom Roy MD, MSc

  • Showrunner: Carolyn Chan, MD, MHS

  • Technical Production: PodPaste

  • Guest: Jessica Merlin MD, PhD, MBA





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#487 Chronic Pain & Opioid Use Disorder with Dr. Jessie Merlin

#487 Chronic Pain & Opioid Use Disorder with Dr. Jessie Merlin

The Curbsiders Internal Medicine Podcast