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Diagnosis and Management of Hypothyroidism

Diagnosis and Management of Hypothyroidism

Update: 2025-09-03
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Untreated hypothyroidism can cause serious health complications such as heart failure and myxedema coma. Author Maria Papaleontiou, MD, of the University of Michigan joins JAMA Senior Editor Karen Lasser, MD, MPH, to discuss the current evidence regarding the epidemiology, diagnosis, clinical presentation, and treatment of primary overt hypothyroidism in nonpregnant adults.

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Diagnosis and Management of Hypothyroidism

Diagnosis and Management of Hypothyroidism