In this episode, I discuss cannabis (aka marijuana), including the biological mechanisms underlying its effects on the mind and body, its known medical applications, its impact on libido, creativity, hunger, hormones and more. I also cover the known adverse health consequences of chronic and even acute (one-time) use and the factors that determine if cannabis is helpful or harmful. Additionally, I detail how the various strains of cannabis: sativa, indica and hybrid strains, can produce such divergent effects depending on the strain type, THC-to-CBD ratio, total dosage, and frequency of use. I review why cannabis can impact speech patterns and one’s propensity to develop anxiety/depression during and after use and, in some individuals, paranoia. As the legal landscape for cannabis is rapidly evolving, this episode should interest a wide audience, including former/current cannabis users, those in the medical, sports, law enforcement, and educational communities and, of course, children, teenagers, and parents.

For the full show notes, visit hubermanlab.com.

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Timestamps

(00:00:00 ) Cannabis (Marijuana)

(00:04:46 ) New: Huberman Lab Premium

(00:07:03 ) Tool: Non-Sleep Deep Rest (NSDR), Sleep & Anxiety

(00:10:08 ) Levels, Thesis, InsideTracker

(00:14:01 ) Momentous Supplements

(00:15:08 ) Cannabis Strains, Psychoactive Compounds: THC & CBD

(00:19:34 ) Sativa vs. Indica, Stimulant vs. Relaxation Effects

(00:25:55 ) Hybrid Cannabis Strains, Type 1, 2 & 3 Strains

(00:30:41 ) AG1 (Athletic Greens)

(00:31:56 ) Naturally Occurring Receptors: Nicotinic & Cannabinoid Receptors (CB1)

(00:40:35 ) THC, CBD vs. Endogenous Cannabinoids, Dependence

(00:43:14 ) Endogenous Cannabinoids, Cannabinoid Receptors & Nervous System Function

(00:53:07 ) Biological Effects of Cannabis

(00:56:29 ) Cannabis Sativa & Subjective Effects: Mood, Stress, Alertness, Paranoia

(01:04:58 ) Cannabis Indica & Subjective Effects, Memory, Dosage

(01:09:41 ) Brain Areas Affected by THC & CBD, Side Effects

(01:16:08 ) Creativity: Convergent vs. Divergent Thinking & Dopamine

(01:26:41 ) Does Cannabis Increase Creativity?

(01:35:08 ) Chronic Cannabis Use & Changes in Speech Patterns

(01:46:46 ) Cannabis & Libido, Dopamine & Prolactin

(01:56:55 ) Cannabis & Hormones: Prolactin, Testosterone, Estrogen & Fertility

(02:06:53 ) Smoking/Vaping Tobacco or Cannabis & Negative Health Consequences

(02:10:06 ) Avoiding Cannabis During Pregnancy/Breastfeeding, Fetal Neural Development

(02:18:13 ) Negative Health Consequences of Cannabis, Anxiety & Depression, Tolerance

(02:25:57 ) Cannabis Use & Adolescence/Young Adulthood, Predisposition to Psychosis

(02:34:36 ) Adolescent Cannabis Use: Brain Development & Mental Health Disorders

(02:41:44 ) Cannabis & Pain Management, Divergent Effects of Cannabis

(02:44:54 ) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Huberman Lab Premium, Momentous Supplements, Neural Network Newsletter, Instagram, Twitter, Facebook, LinkedIn

 Title Card Photo Credit: Mike Blabac

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