In his weekly clinical update, Dr. Griffin and Vincent Racaniello wish everyone a Happy Thanksgiving and then decry appointment of the Louisiana State surgeon general as deputy chief of the CDC, the 3 children's deaths during this fall's pertussis outbreak, the Marburg virus outbreak in Ethiopia, results of the phase 1 safety trial for the novel poliovirus vaccines nOPV1 and nOPV3, and the first human death from H5N5 influenza virus infection in the US this fall, before Dr. Griffin deep dives into recent statistics on the measles epidemic, RSV, influenza and SARS-CoV-2 infections, the Wasterwater Scan dashboard, Johns Hopkins measles tracker, effectiveness of the cell or egg based flu or the mRNA vaccines, immunogenicity and efficacy of updated COVID-19 vaccines, where to find PEMGARDA, how to access and pay for Paxlovid, long COVID treatment center, where to go for answers to your long COVID questions, immune and cognitive dysfunction during long COVID and contacting your federal government representative to stop the assault on science and biomedical research.

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Links for this episode

• Anti-science Movement: Deputy director of CDC (X:Louisiana Office of the Surgeon General)
• CDC's new deputy director is vocal critic of vaccines, advocated for ivermectin (CIDRAP)
• Whooping cough cases on the rise in Texas (FOX4: KDFW)
• Third infant in Kentucky dies of whooping cough as national cases stay high for second year in a row (CIDRAP)
• More than 25,000 whooping cough cases reported this year as Kentucky records 3rd infant death (ABC News)
• Vaccination Coverage and Exemptions among Kindergartners (CDC: SchoolVaxView)
• Effects of human papillomavirus (HPV) vaccination programmes on community rates of HPV‐related disease and harms from vaccination (Cochrane Library)
• Marburg Outbreak in Ethiopia: Current Situation (CDC: Marburg Virus Disease)
• Safety and immunogenicity of novel live attenuated type 1 and type 3 oral poliomyelitis vaccines in healthy adults in the USA: a first-in-human, observer-masked, multicentre, phase 1 randomised controlled trial (LANCET: Infectious Diseases)
• Washington state resident believed to be the first to die from a rare strain of bird flu (AP News)
• Wastewater for measles (WasterWater Scan)
• Measles cases and outbreaks (CDC Rubeola)
• Tracking Measles Cases in the U.S. (Johns Hopkins)
• Measles vaccine recommendations from NYP (jpg)
• Weekly measles and rubella monitoring (Government of Canada)
• Measles (WHO)
• Get the FACTS about measles (NY State Department of Health)
• Measles (CDC Measles (Rubeola))
• Measles vaccine (CDC Measles (Rubeola))
• Presumptive evidence of measles immunity (CDC)
• Contraindications and precautions to measles vaccination (CDC)
• Adverse events associated with childhood vaccines: evidence bearing on causality (NLM)
• Measles Vaccination: Know the Facts (ISDA: Infectious Diseases Society of America)
• Deaths following vaccination: what does the evidence show (Vaccine)
• Influenza: Waste water scan for 11 pathogens (WastewaterSCan)
• US respiratory virus activity (CDC Respiratory Illnesses)
• Respiratory virus activity levels (CDC Respiratory Illnesses)
• Weekly surveillance report: clift notes (CDC FluView)
• Superior Effectiveness and Estimated Public Health Impact of Cell- Versus Egg-Based Influenza Vaccines in Children and Adults During the US 2023–2024 Season (Infectious Diseases and Therapy)
• Efficacy, Immunogenicity, and Safety of Modified mRNA Influenza Vaccine(NEJM)
• ACIP Recommendations Summary (CDC: Influenza)
• Types of Influenza Viruses (CDC: Influenza (flu))
• Influenza Vaccine Composition for the <a href="https://www.fda.gov/vaccines-blood-biologics/influenza-vaccine-composition-2025-2